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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730892
Species: Homo sapiens
RGD Object: Gene
Symbol: NFKB1
Name: nuclear factor kappa B subunit 1
Acc ID: CHEBI:16494
Term: lipoic acid
Definition: A heterocyclic thia fatty acid comprising pentanoic acid with a 1,2-dithiolan-3-yl group at the 5-position.
Chemical ID: MESH:D008063
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NFKB1multiple interactionsEXP 6480464CTDThioctic Acid inhibits the reaction [Zinc deficiency affects the localization of NFKB1 protein]PMID:21600978
NFKB1multiple interactionsISONfkb1 (Rattus norvegicus)6480464CTD[Thioctic Acid co-treated with Propylthiouracil] results in decreased expression of NFKB1 mRNAPMID:31068541
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