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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735634
Species: Mus musculus
RGD Object: Gene
Symbol: Scarb1
Name: scavenger receptor class B, member 1
Acc ID: CHEBI:16325
Term: lithocholic acid
Definition: A monohydroxy-5beta-cholanic acid with a alpha-hydroxy substituent at position 3. It is a bile acid obtained from chenodeoxycholic acid by bacterial action.
Chemical ID: MESH:D008095
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scarb1increases expressionEXP 6480464CTDLithocholic Acid results in increased expression of SCARB1 mRNAPMID:19000923
Scarb1decreases expressionISOSCARB1 (Homo sapiens)6480464CTDLithocholic Acid results in decreased expression of SCARB1 mRNA; Lithocholic Acid results in decreased expression of SCARB1 proteinPMID:15883047
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