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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735801
Species: Homo sapiens
RGD Object: Gene
Symbol: ACTB
Name: actin beta
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ACTBaffects bindingEXP 6480464CTDQuercetin analog binds to ACTB protein mutant formPMID:21798748
ACTBdecreases expressionEXP 6480464CTDQuercetin results in decreased expression of ACTB mRNAPMID:21632981
ACTBmultiple interactionsISOActb (Rattus norvegicus)6480464CTDQuercetin inhibits the reaction [3,4-Dihydroxyphenylacetic Acid analog binds to ACTB protein]PMID:19743802
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