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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631345
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcg2
Name: ATP binding cassette subfamily G member 2
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcg2affects exportEXP 6480464CTDABCG2 protein affects the export of Quercetin metabolitePMID:15749994
Abcg2affects exportISOAbcg2 (Mus musculus)6480464CTDABCG2 protein affects the export of QuercetinPMID:15749994
Abcg2affects expressionISOABCG2 (Homo sapiens)6480464CTDQuercetin affects the expression of ABCG2 mRNAPMID:21632981
Abcg2decreases expressionISOABCG2 (Homo sapiens)6480464CTDQuercetin results in decreased expression of ABCG2 mRNA; Quercetin results in decreased expression of ABCG2 proteinPMID:18624906
Abcg2increases expressionISOABCG2 (Homo sapiens)6480464CTDQuercetin results in increased expression of ABCG2 mRNA; Quercetin results in increased expression of ABCG2 proteinPMID:17077187
Abcg2multiple interactionsISOABCG2 (Homo sapiens)6480464CTDAHR protein promotes the reaction [Quercetin results in increased expression of ABCG2 protein]PMID:17077187
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