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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1317581
Species: Mus musculus
RGD Object: Gene
Symbol: Tnfrsf10b
Name: tumor necrosis factor receptor superfamily, member 10b
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfrsf10baffects localizationISOTNFRSF10A (Homo sapiens)6480464CTDQuercetin affects the localization of TNFRSF10A proteinPMID:17876056
Tnfrsf10bincreases expressionISOTNFRSF10A (Homo sapiens)6480464CTDQuercetin results in increased expression of TNFRSF10A mRNA; Quercetin results in increased expression of TNFRSF10A proteinPMID:17548900 PMID:21632981
Tnfrsf10bmultiple interactionsISOTNFRSF10A (Homo sapiens)6480464CTDNystatin inhibits the reaction [Quercetin affects the localization of TNFRSF10A protein]; Quercetin promotes the reaction [TNFSF10 protein affects the localization of TNFRSF10A protein]PMID:17876056
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