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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10289
Species: Mus musculus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:16196
Term: oleic acid
Definition: An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry.
Chemical ID: MESH:D019301
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3multiple interactionsEXP 6480464CTDOleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased cleavage of CASP3 protein]PMID:32976987
Casp3increases cleavageISOCASP3 (Homo sapiens)6480464CTDOleic Acid results in increased cleavage of CASP3 proteinPMID:36273635
Casp3multiple interactionsISOCASP3 (Homo sapiens)6480464CTD3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP3 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP3 mRNAPMID:32369900
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