GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pdx1 | decreases expression | EXP | | 6480464 | CTD | Palmitic Acid results in decreased expression of PDX1 protein | PMID:19513971 PMID:22819839 | Pdx1 | multiple interactions | EXP | | 6480464 | CTD | 3-aminobenzamide inhibits the reaction [Palmitic Acid results in decreased expression of PDX1 protein]; geniposide inhibits the reaction [Palmitic Acid results in decreased expression of PDX1 protein] | PMID:19513971 PMID:22819839 | Pdx1 | decreases expression | ISO | PDX1 (Homo sapiens) | 6480464 | CTD | Palmitic Acid results in decreased expression of PDX1 mRNA | PMID:18155663 | Pdx1 | multiple interactions | ISO | PDX1 (Homo sapiens) | 6480464 | CTD | Palmitic Acid inhibits the reaction [Glucose affects the localization of PDX1 protein] | PMID:22558381 | Pdx1 | multiple interactions | ISO | Pdx1 (Mus musculus) | 6480464 | CTD | Palmitic Acid inhibits the reaction [Glucose results in increased expression of PDX1 mRNA] | PMID:22558381 | |
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