GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il18 | increases expression | ISO | IL18 (Homo sapiens) | 6480464 | CTD | Acrolein results in increased expression of IL18 protein | PMID:36055550 | Il18 | multiple interactions | ISO | IL18 (Homo sapiens) | 6480464 | CTD | 3-methyladenine promotes the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein]; [Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein; Acetylcysteine inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of IL18 protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of IL18 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of IL18 protein]]; Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of IL18 protein]; belnacasan inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein]; Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of IL18 protein]; NLRP3 protein affects the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein]; Rotenone promotes the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased cleavage of IL18 protein]; Rotenone promotes the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein]; Sirolimus inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein] | PMID:30205151 PMID:36055550 | | ||||||||||||||||||||||
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