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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734431
Species: Homo sapiens
RGD Object: Gene
Symbol: NFE2L2
Name: NFE2 like bZIP transcription factor 2
Acc ID: CHEBI:135338
Term: guggulsterone
Definition: null
Chemical ID: MESH:C023617
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NFE2L2affects response to substanceISONfe2l2 (Mus musculus)6480464CTDNFE2L2 protein affects the susceptibility to pregna-4,17-diene-3,16-dionePMID:22851183
NFE2L2multiple interactionsISONfe2l2 (Mus musculus)6480464CTDpregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate inhibits the reaction [Carbon Tetrachloride results in decreased expression of NFE2L2 mRNA]]PMID:37573684
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