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GENE - TERM ANNOTATION REPORT

RGD ID: 8793780
Species: Chinchilla lanigera
RGD Object: Gene
Symbol: Jup
Name: junction plakoglobin
Acc ID: DOID:9008939
Term: Breast Neoplasms
Definition: Tumors or cancer of the human BREAST.
Definition Source(s): MESH:D001943
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Jup ISOJUP (Homo sapiens)9068941RGDDNA:loss of heterozygosity:tumor:in individuals carrying the BRCA1 predispositionPMID:7604000 REF_RGD_ID:2291881
Jupno_associationISOJUP (Homo sapiens)9068941RGDProtein::tumor:normal expression in both T1 and T2 tumorsPMID:17008277 REF_RGD_ID:2291883
JupseverityISOJUP (Homo sapiens)9068941RGDprotein:increased expression:tumor, cell membrane:significantly associated with relapse-free and overall survival (p=0.029 and 0.020, respectively)PMID:11276001 REF_RGD_ID:2291873
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