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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737309
Species: Homo sapiens
RGD Object: Gene
Symbol: PPARA
Name: peroxisome proliferator activated receptor alpha
Acc ID: CHEBI:64243
Term: monosodium L-glutamate
Definition: An optically active form of monosodium glutamate having L-configuration.
Chemical ID: MESH:D012970
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PPARAdecreases expressionISOPpara (Rattus norvegicus)6480464CTDSodium Glutamate results in decreased expression of PPARA mRNAPMID:21999347
PPARAincreases expressionISOPpara (Mus musculus)6480464CTDSodium Glutamate results in increased expression of PPARA mRNAPMID:21205225 PMID:21549692
PPARAmultiple interactionsISOPpara (Mus musculus)6480464CTD[Bezafibrate co-treated with Sodium Glutamate] results in increased expression of PPARA mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PPARA mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of PPARA mRNAPMID:21549692 PMID:23783067
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