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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736949
Species: Mus musculus
RGD Object: Gene
Symbol: Ppp1r1b
Name: protein phosphatase 1, regulatory inhibitor subunit 1B
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppp1r1bdecreases expressionISOPPP1R1B (Homo sapiens)6480464CTDsodium arsenite results in decreased expression of PPP1R1B mRNAPMID:29301061
Ppp1r1bdecreases phosphorylationISOPpp1r1b (Rattus norvegicus)6480464CTDsodium arsenite results in decreased phosphorylation of PPP1R1B proteinPMID:27966075
Ppp1r1bmultiple interactionsISOPpp1r1b (Rattus norvegicus)6480464CTDCurcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of PPP1R1B protein]PMID:27966075
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