GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CXCL2 | increases expression | ISO | Cxcl2 (Rattus norvegicus) | 6480464 | CTD | 1-Naphthylisothiocyanate results in increased expression of CXCL2 mRNA; 1-Naphthylisothiocyanate results in increased expression of CXCL2 protein | PMID:18364083 PMID:18590720 PMID:25051504 | CXCL2 | increases expression | ISO | Cxcl2 (Mus musculus) | 6480464 | CTD | 1-Naphthylisothiocyanate results in increased expression of CXCL2 mRNA; 1-Naphthylisothiocyanate results in increased expression of CXCL2 protein | PMID:15130876 PMID:20594950 PMID:21070799 PMID:22094456 PMID:27853831 PMID:36460194 | CXCL2 | multiple interactions | ISO | Cxcl2 (Rattus norvegicus) | 6480464 | CTD | Dexamethasone promotes the reaction [1-Naphthylisothiocyanate results in increased expression of CXCL2 mRNA]; Emodin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of CXCL2 mRNA] | PMID:18590720 | CXCL2 | multiple interactions | ISO | Cxcl2 (Mus musculus) | 6480464 | CTD | 3-(5-(4-(cyclopentyloxy)-2-hydroxybenzoyl)-2-((3-hydroxy-1,2-benzisoxazol-6-yl)methoxy)phenyl)propionic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of CXCL2 mRNA]; [3-(5-(4-(cyclopentyloxy)-2-hydroxybenzoyl)-2-((3-hydroxy-1,2-benzisoxazol-6-yl)methoxy)phenyl)propionic acid co-treated with C188-9 compound] inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of CXCL2 mRNA]; [FGA gene mutant form results in increased susceptibility to 1-Naphthylisothiocyanate] which results in increased expression of CXCL2 mRNA; [Progesterone co-treated with 1-Naphthylisothiocyanate] results in increased expression of CXCL2 mRNA; C188-9 compound inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of CXCL2 mRNA]; pirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of CXCL2 mRNA]; PPARA protein affects the reaction [pirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of CXCL2 mRNA]] | PMID:21356363 PMID:22157104 PMID:27853831 PMID:36460194 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |