GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | LDLR | increases expression | EXP | | 6480464 | CTD | Ethinyl Estradiol results in increased expression of LDLR protein | PMID:17900441 | LDLR | multiple interactions | EXP | | 6480464 | CTD | [Desogestrel co-treated with Ethinyl Estradiol] results in increased expression of LDLR protein; [Levonorgestrel co-treated with Ethinyl Estradiol] results in decreased expression of LDLR protein | PMID:17900441 | LDLR | affects expression | ISO | Ldlr (Rattus norvegicus) | 6480464 | CTD | Ethinyl Estradiol affects the expression of LDLR mRNA | PMID:17351261 | LDLR | increases expression | ISO | Ldlr (Rattus norvegicus) | 6480464 | CTD | Ethinyl Estradiol results in increased expression of LDLR mRNA; Ethinyl Estradiol results in increased expression of LDLR protein | PMID:12475377 PMID:12963437 PMID:16940010 | |
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