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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735594
Species: Homo sapiens
RGD Object: Gene
Symbol: LDLR
Name: low density lipoprotein receptor
Acc ID: CHEBI:48720
Term: argatroban
Definition: An alpha-N-substituted L-arginine that has formula C23H36N6O5S.
Chemical ID: MESH:C031942
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
LDLRmultiple interactionsISOLdlr (Mus musculus)6480464CTDargatroban inhibits the reaction [[LDLR gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of Cholesterol]; argatroban inhibits the reaction [[LDLR gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of Triglycerides]PMID:22841818
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