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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735505
Species: Homo sapiens
RGD Object: Gene
Symbol: AQP9
Name: aquaporin 9
Acc ID: CHEBI:31823
Term: mercury dichloride
Definition: A mercury coordination entity made up of linear triatomic molecules in which a mercury atom is bonded to two chlorines. Water-soluble, it is highly toxic. Once used in a wide variety of applications, including preserving wood and anatomical specimens, embalming and disinfecting, as an intensifier in photography, as a mordant for rabbit and beaver furs, and freeing gold from lead, its use has markedly declined as less toxic alternatives have been developed.
Chemical ID: MESH:D008627
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AQP9decreases activityEXP 6480464CTDMercuric Chloride results in decreased activity of AQP9 proteinPMID:9514918
AQP9multiple interactionsEXP 6480464CTDMercuric Chloride inhibits the reaction [AQP9 protein results in increased transport of Water]PMID:9514918
AQP9decreases activityISOAqp9 (Rattus norvegicus)6480464CTDMercuric Chloride results in decreased activity of AQP9 proteinPMID:9733774
AQP9multiple interactionsISOAqp9 (Rattus norvegicus)6480464CTDMercuric Chloride inhibits the reaction [AQP9 protein results in increased transport of Water]PMID:10205677 PMID:22114114 PMID:9733774
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