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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735504
Species: Homo sapiens
RGD Object: Gene
Symbol: C3
Name: complement C3
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
C3affects methylationEXP 6480464CTDsodium arsenite affects the methylation of C3 genePMID:28589171
C3decreases expressionEXP 6480464CTDsodium arsenite results in decreased expression of C3 mRNAPMID:38568856
C3affects expressionISOC3 (Mus musculus)6480464CTDsodium arsenite affects the expression of C3 mRNAPMID:17450228
C3decreases expressionISOC3 (Mus musculus)6480464CTDsodium arsenite results in decreased expression of C3 mRNAPMID:37682722
C3decreases expressionISOC3 (Rattus norvegicus)6480464CTDsodium arsenite results in decreased expression of C3 proteinPMID:31874112
C3increases activityISOC3 (Rattus norvegicus)6480464CTDsodium arsenite results in increased activity of C3 protein modified formPMID:20946910
C3increases expressionISOC3 (Mus musculus)6480464CTDsodium arsenite results in increased expression of C3 mRNAPMID:21911445
C3multiple interactionsISOC3 (Rattus norvegicus)6480464CTD[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of C3 protein modified form]PMID:20946910
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