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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733118
Species: Mus musculus
RGD Object: Gene
Symbol: Cxcl2
Name: C-X-C motif chemokine ligand 2
Acc ID: CHEBI:30052
Term: copper(0)
Definition: An elemental copper that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cxcl2increases expressionEXP 6480464CTDCopper results in increased expression of CXCL2 mRNAPMID:21765606
Cxcl2multiple interactionsEXP 6480464CTD(4-(((2-(3-fluoro-4-(trifluoromethyl)phenyl)-4-methyl-1,3-thiazol-5-yl)methyl)sulfanyl)-2-methylphenoxy)acetic acid inhibits the reaction [Copper results in increased expression of CXCL2 mRNA]; GSK0660 promotes the reaction [Copper results in increased expression of CXCL2 mRNA]PMID:21765606
Cxcl2multiple interactionsISOCXCL2 (Homo sapiens)6480464CTD[Chelating Agents binds to Copper] which affects the expression of CXCL2 mRNA; [NSC 689534 binds to Copper] which results in increased expression of CXCL2 mRNAPMID:20971185 PMID:30911355
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