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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732751
Species: Homo sapiens
RGD Object: Gene
Symbol: NR4A1
Name: nuclear receptor subfamily 4 group A member 1
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NR4A1decreases expressionEXP 6480464CTDEstradiol results in decreased expression of NR4A1 mRNAPMID:16514628
NR4A1increases expressionEXP 6480464CTDEstradiol results in increased expression of NR4A1 mRNAPMID:31614463
NR4A1multiple interactionsEXP 6480464CTD[Estradiol co-treated with TGFB1 protein] results in decreased expression of NR4A1 mRNAPMID:30165855
NR4A1affects expressionISONr4a1 (Rattus norvegicus)6480464CTDEstradiol affects the expression of NR4A1 mRNAPMID:32145629
NR4A1affects expressionISONr4a1 (Mus musculus)6480464CTDEstradiol affects the expression of NR4A1 mRNAPMID:15598610
NR4A1decreases expressionISONr4a1 (Rattus norvegicus)6480464CTDEstradiol results in decreased expression of NR4A1 mRNAPMID:20068009
NR4A1increases expressionISONr4a1 (Mus musculus)6480464CTDEstradiol results in increased expression of NR4A1 mRNAPMID:20667977 PMID:20826375 PMID:32186404
NR4A1multiple interactionsISONr4a1 (Mus musculus)6480464CTDESR1 protein promotes the reaction [Estradiol results in increased expression of NR4A1 mRNA]PMID:20667977
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