GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | GSR | increases activity | EXP | | 6480464 | CTD | resveratrol analog results in increased activity of GSR protein; resveratrol results in increased activity of GSR protein | PMID:12797471 PMID:24398169 | GSR | increases expression | EXP | | 6480464 | CTD | resveratrol results in increased expression of GSR mRNA | PMID:12002526 PMID:12569576 | GSR | multiple interactions | EXP | | 6480464 | CTD | [Plant Extracts co-treated with Resveratrol] results in increased expression of GSR mRNA | PMID:23557933 | GSR | increases activity | ISO | Gsr (Rattus norvegicus) | 6480464 | CTD | resveratrol results in increased activity of GSR protein | PMID:16169743 | GSR | increases expression | ISO | Gsr (Mus musculus) | 6480464 | CTD | resveratrol results in increased expression of GSR protein | PMID:25952010 | GSR | multiple interactions | ISO | Gsr (Rattus norvegicus) | 6480464 | CTD | [Niacinamide co-treated with Resveratrol] inhibits the reaction [[Ethanol co-treated with Aflatoxin B1] results in decreased expression of GSR protein]; Resveratrol inhibits the reaction [1,2-Dimethylhydrazine results in decreased activity of GSR protein]; Resveratrol inhibits the reaction [[Ethanol co-treated with Aflatoxin B1] results in decreased expression of GSR protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein]; Resveratrol inhibits the reaction [APP protein modified form results in decreased activity of GSR protein]; Resveratrol inhibits the reaction [Fenitrothion results in decreased expression of GSR protein] | PMID:19523937 PMID:20307516 PMID:21439372 PMID:25654502 PMID:32894639 PMID:34968465 | GSR | multiple interactions | ISO | Gsr (Mus musculus) | 6480464 | CTD | [Curcumin co-treated with resveratrol] inhibits the reaction [Benzo(a)pyrene results in decreased activity of GSR protein]; NFE2L2 protein promotes the reaction [resveratrol promotes the reaction [Azoxymethane results in increased expression of GSR mRNA]]; resveratrol inhibits the reaction [Ethanol results in decreased activity of GSR protein]; resveratrol inhibits the reaction [Pyrogallol results in decreased activity of GSR protein]; resveratrol promotes the reaction [Azoxymethane results in increased expression of GSR mRNA] | PMID:18789925 PMID:21086752 PMID:21355597 PMID:25632966 | | ||||||||||||||||||||||
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