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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732106
Species: Mus musculus
RGD Object: Gene
Symbol: Fadd
Name: Fas associated via death domain
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fadddecreases expressionISOFADD (Homo sapiens)6480464CTDbisphenol A results in decreased expression of FADD mRNA; bisphenol A results in decreased expression of FADD proteinPMID:21277958 PMID:36982678
Fadddecreases expressionISOFadd (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of FADD mRNAPMID:25181051
Faddincreases expressionISOFadd (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of FADD mRNAPMID:30816183 PMID:31771501 PMID:32528016
Faddmultiple interactionsISOFADD (Homo sapiens)6480464CTD[bisphenol A results in decreased expression of MIR27B] which results in increased expression of FADD mRNA; [naringenin metabolite co-treated with bisphenol A] results in increased expression of FADD mRNAPMID:30690568 PMID:36235125
Faddmultiple interactionsISOFadd (Rattus norvegicus)6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of FADD mRNAPMID:36041667
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