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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731970
Species: Homo sapiens
RGD Object: Gene
Symbol: DEAF1
Name: DEAF1 transcription factor
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
DEAF1increases methylationEXP 6480464CTDValproic Acid results in increased methylation of DEAF1 genePMID:29154799
DEAF1decreases expressionISODeaf1 (Mus musculus)6480464CTDValproic Acid results in decreased expression of DEAF1 mRNAPMID:19136453 PMID:21427059
DEAF1increases expressionISODeaf1 (Mus musculus)6480464CTDValproic Acid results in increased expression of DEAF1 mRNAPMID:21427059
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