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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731438
Species: Homo sapiens
RGD Object: Gene
Symbol: MYC
Name: MYC proto-oncogene, bHLH transcription factor
Acc ID: CHEBI:35559
Term: furan
Definition: A monocyclic heteroarene with a structure consisting of a 5-membered ring containing four carbons and one oxygen, with formula C4H4O. It is a toxic, flammable, low-boiling (31degreeC) colourless liquid.
Chemical ID: MESH:C039281
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MYCdecreases expressionISOMyc (Rattus norvegicus)6480464CTDfuran results in decreased expression of MYC mRNAPMID:25539665
MYCincreases expressionISOMyc (Mus musculus)6480464CTDfuran results in increased expression of MYC mRNAPMID:24183702 PMID:24910943 PMID:37517673
MYCincreases expressionISOMyc (Rattus norvegicus)6480464CTDfuran results in increased expression of MYC mRNAPMID:20124500
MYCmultiple interactionsISOMyc (Mus musculus)6480464CTD[Bromodeoxyuridine co-treated with furan] results in increased expression of MYC mRNAPMID:24910943
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