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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731060
Species: Mus musculus
RGD Object: Gene
Symbol: Rhoa
Name: ras homolog family member A
Acc ID: CHEBI:15420
Term: perillyl alcohol
Definition: A limonene monoterpenoid consists of a cyclohexene ring substituted by a hydroxymethyl and a prop-1-en-2-yl group at positions 1 and 4 respectively. It is a constituent of a variety of essential oils including lavender.
Chemical ID: MESH:C032208
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rhoaincreases expressionISORHOA (Homo sapiens)6480464CTDperillyl alcohol results in increased expression of RHOA proteinPMID:12671036
Rhoamultiple interactionsISORHOA (Homo sapiens)6480464CTDMevalonic Acid affects the reaction [perillyl alcohol results in increased expression of RHOA protein]PMID:12671036
Rhoamultiple interactionsISORhoa (Rattus norvegicus)6480464CTD[perillyl alcohol co-treated with Vitamin A] results in increased expression of RHOA mRNAPMID:15959631
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