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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730981
Species: Homo sapiens
RGD Object: Gene
Symbol: IL1B
Name: interleukin 1 beta
Acc ID: CHEBI:4975
Term: famotidine
Definition: A guanidine that has formula C8H15N7O2S3.
Chemical ID: MESH:D015738
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL1Bmultiple interactionsEXP 6480464CTD[Famotidine co-treated with Sucralfate] results in decreased expression of IL1B mRNAPMID:17717918
IL1Bmultiple interactionsISOIl1b (Rattus norvegicus)6480464CTDFamotidine inhibits the reaction [Ethanol results in increased expression of IL1B protein]; Famotidine inhibits the reaction [Indomethacin results in increased expression of IL1B mRNA]PMID:27474069 PMID:27645307
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