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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730872
Species: Homo sapiens
RGD Object: Gene
Symbol: SOD2
Name: superoxide dismutase 2
Acc ID: CHEBI:28216
Term: methylmercury chloride
Definition: A chlorine molecular entity that has formula CH3ClHg.
Chemical ID: MESH:C004925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SOD2decreases expressionEXP 6480464CTDmethylmercuric chloride results in decreased expression of SOD2 mRNAPMID:29581082
SOD2increases expressionEXP 6480464CTDmethylmercuric chloride results in increased expression of SOD2 mRNAPMID:28001369
SOD2decreases activityISOSod2 (Mus musculus)6480464CTDmethylmercuric chloride results in decreased activity of SOD2 proteinPMID:21781743
SOD2decreases expressionISOSod2 (Mus musculus)6480464CTDmethylmercuric chloride results in decreased expression of SOD2 mRNA; methylmercuric chloride results in decreased expression of SOD2 proteinPMID:33301842
SOD2decreases expressionISOSod2 (Rattus norvegicus)6480464CTDmethylmercuric chloride results in decreased expression of SOD2 proteinPMID:29258870
SOD2increases expressionISOSod2 (Mus musculus)6480464CTDmethylmercuric chloride results in increased expression of SOD2 proteinPMID:33338554
SOD2multiple interactionsISOSod2 (Mus musculus)6480464CTD[GHRL protein co-treated with methylmercuric chloride] results in decreased expression of SOD2 proteinPMID:33301842
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