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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727911
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Amigo2
Name: adhesion molecule with Ig like domain 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Amigo2affects expressionISOAmigo2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of AMIGO2 mRNAPMID:24680724
Amigo2affects expressionISOAMIGO2 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin affects the expression of AMIGO2 mRNAPMID:22298810
Amigo2decreases expressionISOAmigo2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of AMIGO2 mRNAPMID:26290441
Amigo2decreases expressionISOAMIGO2 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of AMIGO2 mRNAPMID:19619570 PMID:20106945
Amigo2multiple interactionsISOAmigo2 (Mus musculus)6480464CTD[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of AMIGO2 mRNAPMID:25975270
Amigo2multiple interactionsISOAMIGO2 (Homo sapiens)6480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of AMIGO2 mRNAPMID:19619570
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