Amigo2 (adhesion molecule with Ig like domain 2) - Rat Genome Database

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Gene: Amigo2 (adhesion molecule with Ig like domain 2) Mus musculus
Analyze
Symbol: Amigo2
Name: adhesion molecule with Ig like domain 2
RGD ID: 1553273
MGI Page MGI
Description: Acts upstream of or within positive regulation of synapse assembly. Predicted to be located in membrane. Is expressed in several structures, including brain; branchial arch; cranial ganglion; genitourinary system; and retina. Orthologous to human AMIGO2 (adhesion molecule with Ig like domain 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI415330; Ali1; alivin 1; alivin-1; AMIGO-2; amphoterin induced gene and ORF 2; amphoterin-induced protein 2; AW208913
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391597,141,955 - 97,145,168 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1597,142,006 - 97,145,168 (-)EnsemblGRCm39 Ensembl
GRCm381597,244,074 - 97,247,287 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1597,244,125 - 97,247,287 (-)EnsemblGRCm38mm10GRCm38
MGSCv371597,074,505 - 97,077,718 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361597,072,159 - 97,075,156 (-)NCBIMGSCv36mm8
Celera1599,379,756 - 99,382,756 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1552.91NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dinitrotoluene  (ISO)
2-palmitoylglycerol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
6alpha-methylprednisolone  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
aristolochic acid A  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (EXP)
cefaloridine  (ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (EXP)
dieldrin  (ISO)
diethyl maleate  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
ethanol  (EXP)
genistein  (ISO)
gentamycin  (ISO)
glycidol  (ISO)
indometacin  (ISO)
irinotecan  (ISO)
ketamine  (ISO)
lead(0)  (EXP)
lipopolysaccharide  (ISO)
maneb  (EXP)
mercury dibromide  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-Nitrosopyrrolidine  (ISO)
ochratoxin A  (ISO)
ozone  (EXP)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
phenylmercury acetate  (ISO)
pioglitazone  (EXP)
piroxicam  (ISO)
potassium bromate  (ISO)
potassium chromate  (ISO)
prednisolone  (ISO)
progesterone  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (EXP)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (ISO)
sodium aurothiomalate  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IBA,ISO)
nucleus  (IEA)
plasma membrane  (IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Amigo2-upregulation in Tumour Cells Facilitates Their Attachment to Liver Endothelial Cells Resulting in Liver Metastases. Kanda Y, etal., Sci Rep. 2017 Mar 8;7:43567. doi: 10.1038/srep43567.
2. AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats. Kuja-Panula J, etal., J Cell Biol 2003 Mar 17;160(6):963-73.
3. AMIGO2 modulates T cell functions and its deficiency in mice ameliorates experimental autoimmune encephalomyelitis. Li Z, etal., Brain Behav Immun. 2017 May;62:110-123. doi: 10.1016/j.bbi.2017.01.009. Epub 2017 Feb 1.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. AMIGO2, a novel membrane anchor of PDK1, controls cell survival and angiogenesis via Akt activation. Park H, etal., J Cell Biol. 2015 Nov 9;211(3):619-37. doi: 10.1083/jcb.201503113.
7. DEGA/AMIGO-2, a leucine-rich repeat family member, differentially expressed in human gastric adenocarcinoma: effects on ploidy, chromosomal stability, cell adhesion/migration and tumorigenicity. Rabenau KE, etal., Oncogene. 2004 Jun 24;23(29):5056-67. doi: 10.1038/sj.onc.1207681.
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:12843293   PMID:16141072   PMID:16141073   PMID:18077674   PMID:18848646   PMID:19906978  
PMID:21267068   PMID:21873635   PMID:22314660   PMID:24613359   PMID:25053427   PMID:25826454   PMID:29718531   PMID:29924804   PMID:31693896   PMID:31787886   PMID:35169021   PMID:35727300  


Genomics

Comparative Map Data
Amigo2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391597,141,955 - 97,145,168 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1597,142,006 - 97,145,168 (-)EnsemblGRCm39 Ensembl
GRCm381597,244,074 - 97,247,287 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1597,244,125 - 97,247,287 (-)EnsemblGRCm38mm10GRCm38
MGSCv371597,074,505 - 97,077,718 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361597,072,159 - 97,075,156 (-)NCBIMGSCv36mm8
Celera1599,379,756 - 99,382,756 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1552.91NCBI
AMIGO2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381247,075,707 - 47,079,959 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1247,075,707 - 47,079,959 (-)EnsemblGRCh38hg38GRCh38
GRCh371247,469,490 - 47,473,742 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361245,755,757 - 45,759,915 (-)NCBINCBI36Build 36hg18NCBI36
Build 341245,755,756 - 45,759,915NCBI
Celera1246,266,530 - 46,270,780 (-)NCBICelera
Cytogenetic Map12q13.11NCBI
HuRef1244,500,413 - 44,504,656 (-)NCBIHuRef
CHM1_11247,434,869 - 47,439,118 (-)NCBICHM1_1
T2T-CHM13v2.01247,036,477 - 47,040,734 (-)NCBIT2T-CHM13v2.0
Amigo2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87130,270,639 - 130,273,735 (-)NCBIGRCr8
mRatBN7.27128,391,493 - 128,394,589 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7128,390,412 - 128,394,695 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7130,188,505 - 130,191,609 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07132,414,037 - 132,417,141 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07132,329,495 - 132,332,533 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07138,704,124 - 138,707,221 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7138,704,126 - 138,707,221 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07138,327,613 - 138,330,710 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47135,966,794 - 135,969,747 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17136,043,230 - 136,046,184 (-)NCBI
Celera7124,880,421 - 124,883,447 (-)NCBICelera
Cytogenetic Map7q36NCBI
Amigo2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555006,134,736 - 6,138,075 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555006,134,736 - 6,138,075 (-)NCBIChiLan1.0ChiLan1.0
AMIGO2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21047,087,432 - 47,090,754 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11247,084,383 - 47,087,467 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01241,652,954 - 41,656,393 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11242,525,099 - 42,528,399 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1242,525,858 - 42,527,426 (+)Ensemblpanpan1.1panPan2
AMIGO2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1277,507,426 - 7,510,015 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl277,507,489 - 7,509,054 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2738,798,999 - 38,802,268 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0277,573,450 - 7,576,716 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl277,573,601 - 7,576,762 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1277,509,723 - 7,513,046 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0277,552,000 - 7,555,266 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02739,041,956 - 39,045,226 (-)NCBIUU_Cfam_GSD_1.0
Amigo2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494568,004,585 - 68,007,754 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365125,157,175 - 5,159,818 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365125,157,076 - 5,160,251 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AMIGO2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl577,642,195 - 77,645,753 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1577,642,144 - 77,645,748 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2580,650,537 - 80,653,629 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AMIGO2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11143,281,634 - 43,285,016 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1143,282,518 - 43,284,083 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037203,104,609 - 203,108,095 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Amigo2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248165,184,536 - 5,187,659 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248165,184,423 - 5,189,691 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Amigo2
118 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:290
Count of miRNA genes:202
Interacting mature miRNAs:239
Transcripts:ENSMUST00000053106
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156316390397163995Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577527592104073951Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78601103102901704Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578601103102901704Mouse
14928306Manh79_mmandible shape 79 (mouse)1578847557104073951Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1578897881104073951Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579163411104073951Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined79908940104073951Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580313634104073951Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580884933104073951Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580884933104073951Mouse
4141511Gdcr1_mglycerolphosphate dehydrogenase regulator 1 (mouse)Not determined82615474104073951Mouse
11530037Sluc34a_msusceptibility to lung cancer 34a (mouse)1585896437104073951Mouse
11530038Sluc34b_msusceptibility to lung cancer 34b (mouse)1585896437104073951Mouse
1357614Bmca_mbile mucin accumulation (mouse)Not determined1585896437104073951Mouse
1301918Skull22_mskull morphology 22 (mouse)Not determined1585901546104073951Mouse
4141581Dshv1_mdorsal hippocampal volume 1 (mouse)Not determined92788640103425899Mouse

Markers in Region
AI415330  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381597,244,352 - 97,244,432UniSTSGRCm38
MGSCv371597,074,783 - 97,074,863UniSTSGRCm37
Celera1599,380,034 - 99,380,114UniSTS
Cytogenetic Map15F1UniSTS
Whitehead/MRC_RH15863.8UniSTS
Amigo2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381597,245,458 - 97,246,476UniSTSGRCm38
MGSCv371597,075,889 - 97,076,907UniSTSGRCm37
Celera1599,381,140 - 99,382,158UniSTS
Cytogenetic Map15F1UniSTS
cM Map15 UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000053106   ⟹   ENSMUSP00000059913
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1597,142,025 - 97,145,168 (-)Ensembl
GRCm38.p6 Ensembl1597,244,144 - 97,247,287 (-)Ensembl
RefSeq Acc Id: ENSMUST00000229890   ⟹   ENSMUSP00000155019
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1597,142,006 - 97,145,003 (-)Ensembl
GRCm38.p6 Ensembl1597,244,125 - 97,247,122 (-)Ensembl
RefSeq Acc Id: NM_001164563   ⟹   NP_001158035
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391597,141,955 - 97,145,168 (-)NCBI
GRCm381597,244,074 - 97,247,287 (-)ENTREZGENE
MGSCv371597,074,505 - 97,077,718 (-)RGD
Celera1599,379,756 - 99,382,756 (-)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001164602   ⟹   NP_001158074
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391597,141,955 - 97,145,168 (-)NCBI
GRCm381597,244,074 - 97,247,287 (-)ENTREZGENE
MGSCv371597,074,505 - 97,077,718 (-)RGD
Celera1599,379,756 - 99,382,756 (-)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_178114   ⟹   NP_835215
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391597,141,955 - 97,145,168 (-)NCBI
GRCm381597,244,074 - 97,247,287 (-)ENTREZGENE
MGSCv371597,074,505 - 97,077,718 (-)RGD
Celera1599,379,756 - 99,382,756 (-)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_835215   ⟸   NM_178114
- Peptide Label: precursor
- UniProtKB: Q80ZD9 (UniProtKB/Swiss-Prot),   Q4VBE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001158035   ⟸   NM_001164563
- Peptide Label: precursor
- UniProtKB: Q80ZD9 (UniProtKB/Swiss-Prot),   Q4VBE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001158074   ⟸   NM_001164602
- Peptide Label: precursor
- UniProtKB: Q80ZD9 (UniProtKB/Swiss-Prot),   Q4VBE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000059913   ⟸   ENSMUST00000053106
RefSeq Acc Id: ENSMUSP00000155019   ⟸   ENSMUST00000229890
Protein Domains
Ig-like   Ig-like C2-type   LRRCT   LRRNT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q80ZD9-F1-model_v2 AlphaFold Q80ZD9 1-519 view protein structure

Promoters
RGD ID:6825761
Promoter ID:MM_KWN:19558
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day4,   BoneMarrow_2Hour,   Brain,   Liver,   Lung
Transcripts:NM_001164563,   NM_001164602,   NM_178114
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361597,077,486 - 97,078,472 (-)MPROMDB
RGD ID:8684854
Promoter ID:EPDNEW_M20458
Type:single initiation site
Name:Amigo2_1
Description:Mus musculus adhesion molecule with Ig like domain 2 , transcriptvariant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381597,247,250 - 97,247,310EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2145995 AgrOrtholog
Ensembl Genes ENSMUSG00000048218 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000053106 ENTREZGENE
  ENSMUST00000053106.7 UniProtKB/Swiss-Prot
  ENSMUST00000229890 ENTREZGENE
  ENSMUST00000229890.2 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:105827 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2145995 ENTREZGENE
NCBI Gene 105827 ENTREZGENE
PANTHER IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRRNT DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00047 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Amigo2 PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_TYP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRRCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt AMGO2_MOUSE UniProtKB/Swiss-Prot
  Q4VBE6 ENTREZGENE, UniProtKB/TrEMBL
  Q80ZD9 ENTREZGENE