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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70498
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfkb1
Name: nuclear factor kappa B subunit 1
Acc ID: CHEBI:28527
Term: rutin
Definition: A rutinoside that is quercetin with the hydroxy group at position C-3 substituted with glucose and rhamnose sugar groups.
Chemical ID: MESH:D012431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfkb1multiple interactionsISONFKB1 (Homo sapiens)6480464CTDRutin inhibits the reaction [Hydrogen Peroxide results in increased expression of NFKB1 protein]; Rutin inhibits the reaction [Lipopolysaccharides results in increased expression of NFKB1 mRNA]PMID:38555047
Nfkb1multiple interactionsISONfkb1 (Mus musculus)6480464CTDRutin inhibits the reaction [FAS protein mutant form results in increased expression of NFKB1 protein]PMID:38555047
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