GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapt | decreases expression | ISO | MAPT (Homo sapiens) | 6480464 | CTD | Hydrogen Peroxide results in decreased expression of MAPT mRNA | PMID:31521693 | Mapt | increases phosphorylation | ISO | MAPT (Homo sapiens) | 6480464 | CTD | Hydrogen Peroxide results in increased phosphorylation of MAPT protein | PMID:31173752 | Mapt | multiple interactions | ISO | MAPT (Homo sapiens) | 6480464 | CTD | 4-((alpha-L-rhamnosyloxy)benzyl)isothiocyanate inhibits the reaction [Hydrogen Peroxide results in decreased expression of MAPT mRNA]; Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of MAPT mRNA]; Hydrogen Peroxide promotes the reaction [MAPT results in decreased expression of BCL2 protein]; Hydrogen Peroxide promotes the reaction [MAPT results in increased expression of CDKN2A protein]; Hydrogen Peroxide promotes the reaction [MAPT results in increased expression of RB1 protein]; Hydrogen Peroxide promotes the reaction [MAPT results in increased expression of TP53 protein]; Liraglutide inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPT protein]; Wortmannin inhibits the reaction [Liraglutide inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPT protein]] | PMID:28526263 PMID:31173752 PMID:31521693 | | ||||||||||||||||||||||
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