GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cdkn1a | increases expression | EXP | | 6480464 | CTD | Acrylamide results in increased expression of CDKN1A mRNA; Acrylamide results in increased expression of CDKN1A protein | PMID:28959563 PMID:33582169 | Cdkn1a | multiple interactions | EXP | | 6480464 | CTD | [FOXO3 mRNA co-treated with Acrylamide] results in increased expression of CDKN1A protein; FOXO3 protein promotes the reaction [Acrylamide results in increased expression of CDKN1A mRNA]; MIR193B mRNA inhibits the reaction [Acrylamide results in increased expression of CDKN1A mRNA]; MIR193B mRNA inhibits the reaction [Acrylamide results in increased expression of CDKN1A protein] | PMID:33582169 | Cdkn1a | decreases expression | ISO | CDKN1A (Homo sapiens) | 6480464 | CTD | Acrylamide results in decreased expression of CDKN1A protein modified form | PMID:20734998 | Cdkn1a | increases expression | ISO | Cdkn1a (Mus musculus) | 6480464 | CTD | Acrylamide results in increased expression of CDKN1A protein | PMID:25531190 | Cdkn1a | increases expression | ISO | CDKN1A (Homo sapiens) | 6480464 | CTD | Acrylamide results in increased expression of CDKN1A protein modified form | PMID:20734998 | Cdkn1a | multiple interactions | ISO | Cdkn1a (Mus musculus) | 6480464 | CTD | [Acrylamide co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CDKN1A protein; ATF3 protein promotes the reaction [Acrylamide results in increased expression of CDKN1A protein] | PMID:25531190 PMID:30409764 | | ||||||||||||||||||||||
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