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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69328
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdkn1a
Name: cyclin-dependent kinase inhibitor 1A
Acc ID: CHEBI:28112
Term: nickel atom
Definition: Chemical element (nickel group element atom) with atomic number 28.
Chemical ID: MESH:D009532
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdkn1amultiple interactionsEXP 6480464CTD[Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of CDKN1A mRNA; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of CDKN1A mRNAPMID:22198552
Cdkn1aincreases expressionISOCdkn1a (Mus musculus)6480464CTDNickel results in increased expression of CDKN1A mRNAPMID:12540486
Cdkn1aincreases expressionISOCDKN1A (Homo sapiens)6480464CTDNickel results in increased expression of CDKN1A mRNAPMID:24068677
Cdkn1amultiple interactionsISOCDKN1A (Homo sapiens)6480464CTDTP53 protein affects the reaction [Nickel results in increased expression of CDKN1A mRNA]PMID:24068677
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