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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69328
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdkn1a
Name: cyclin-dependent kinase inhibitor 1A
Acc ID: CHEBI:27363
Term: zinc atom
Definition: A zinc group element atom that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdkn1aincreases expressionEXP 6480464CTDZinc deficiency results in increased expression of CDKN1A mRNA; Zinc results in increased expression of CDKN1A mRNAPMID:17074742 PMID:19111725
Cdkn1amultiple interactionsEXP 6480464CTD[SLC30A10 protein affects the abundance of Zinc] which affects the expression of CDKN1A protein; [SLC30A3 protein affects the abundance of Zinc] which affects the expression of CDKN1A proteinPMID:22427991
Cdkn1aincreases expressionISOCdkn1a (Mus musculus)6480464CTDZinc results in increased expression of CDKN1A proteinPMID:31505237
Cdkn1aincreases expressionISOCDKN1A (Homo sapiens)6480464CTDZinc results in increased expression of CDKN1A mRNA; Zinc results in increased expression of CDKN1A proteinPMID:12107073 PMID:15880691
Cdkn1amultiple interactionsISOCDKN1A (Homo sapiens)6480464CTD[PCI 5002 co-treated with Zinc] results in increased expression of CDKN1A mRNAPMID:18593933
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