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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69328
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdkn1a
Name: cyclin-dependent kinase inhibitor 1A
Acc ID: CHEBI:17598
Term: phorbol 12,13-dibutanoate
Definition: A phorbol ester that has formula C28H40O8.
Chemical ID: MESH:D015240
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdkn1aincreases expressionISOCDKN1A (Homo sapiens)6480464CTDPhorbol 12,13-Dibutyrate results in increased expression of CDKN1A proteinPMID:15014036
Cdkn1amultiple interactionsISOCDKN1A (Homo sapiens)6480464CTDPhorbol 12,13-Dibutyrate inhibits the reaction [alvocidib inhibits the reaction [romidepsin results in increased expression of CDKN1A protein]]PMID:15014036
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