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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69323
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Erbb3
Name: erb-b2 receptor tyrosine kinase 3
Acc ID: CHEBI:41774
Term: tamoxifen
Definition: A stilbenoid that has formula 371.51460.
Chemical ID: MESH:D013629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Erbb3affects expressionISOErbb3 (Mus musculus)6480464CTDTamoxifen affects the expression of ERBB3 mRNAPMID:17555576
Erbb3decreases response to substanceISOERBB3 (Homo sapiens)6480464CTDERBB3 protein results in decreased susceptibility to TamoxifenPMID:16000581
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