GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ager | increases expression | EXP | | 6480464 | CTD | Streptozocin results in increased expression of AGER mRNA; Streptozocin results in increased expression of AGER protein | PMID:22476978 PMID:25199697 PMID:31009641 | Ager | multiple interactions | EXP | | 6480464 | CTD | [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; Kangen-karyu inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of AGER mRNA] | PMID:19397970 PMID:22476978 PMID:25199697 PMID:31009641 PMID:36999408 | Ager | increases expression | ISO | Ager (Mus musculus) | 6480464 | CTD | Streptozocin results in increased expression of AGER mRNA | PMID:19833897 | Ager | increases response to substance | ISO | Ager (Mus musculus) | 6480464 | CTD | AGER protein results in increased susceptibility to Streptozocin | PMID:27109771 | Ager | multiple interactions | ISO | Ager (Mus musculus) | 6480464 | CTD | manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Streptozocin results in increased expression of AGER mRNA] | PMID:19833897 | |
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