GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PPARG | multiple interactions | EXP | | 6480464 | CTD | Acetylcysteine inhibits the reaction [[[15-deoxyprostaglandin J2 results in increased activity of PPARG protein] which results in decreased expression of SOD2 protein] which results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein] | PMID:16945329 PMID:23964924 | PPARG | increases expression | ISO | Pparg (Rattus norvegicus) | 6480464 | CTD | Acetylcysteine results in increased expression of PPARG mRNA; Acetylcysteine results in increased expression of PPARG protein | PMID:17602960 | PPARG | multiple interactions | ISO | Pparg (Rattus norvegicus) | 6480464 | CTD | Acetylcysteine inhibits the reaction [yttrium chloride results in decreased expression of PPARG protein]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in increased expression of PPARG mRNA]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in increased expression of PPARG protein] | PMID:17602960 PMID:35088107 | PPARG | multiple interactions | ISO | Pparg (Mus musculus) | 6480464 | CTD | Acetylcysteine inhibits the reaction [[Carbon Monoxide results in increased abundance of Reactive Oxygen Species] which results in increased sumoylation of PPARG protein]; Acetylcysteine inhibits the reaction [INS1 protein results in increased expression of PPARG protein] | PMID:22046279 PMID:27117918 | | ||||||||||||||||||||||
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