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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69105
Species: Homo sapiens
RGD Object: Gene
Symbol: NR1I2
Name: nuclear receptor subfamily 1 group I member 2
Acc ID: CHEBI:6902
Term: metolachlor
Definition: A racemate that consists of equimolar amounts of (R)- and (S)-metolachlor.
Chemical ID: MESH:C051786
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NR1I2increases activityEXP 6480464CTDmetolachlor results in increased activity of NR1I2 proteinPMID:16565514 PMID:28728110
NR1I2multiple interactionsEXP 6480464CTDmetolachlor binds to and results in increased activity of NR1I2 proteinPMID:21115097 PMID:33049310
NR1I2multiple interactionsISONr1i2 (Mus musculus)6480464CTDmetolachlor binds to and results in increased activity of NR1I2 proteinPMID:21115097 PMID:33049310
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