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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69105
Species: Homo sapiens
RGD Object: Gene
Symbol: NR1I2
Name: nuclear receptor subfamily 1 group I member 2
Acc ID: CHEBI:15948
Term: lycopene
Definition: An acyclic carotene commonly obtained from tomatoes and other red fruits.
Chemical ID: MESH:C015329
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NR1I2increases expressionISONr1i2 (Mus musculus)6480464CTDLycopene results in increased expression of NR1I2 mRNA; Lycopene results in increased expression of NR1I2 proteinPMID:36216167
NR1I2multiple interactionsISONr1i2 (Mus musculus)6480464CTDLycopene inhibits the reaction [Atrazine results in increased expression of NR1I2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of NR1I2 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NR1I2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NR1I2 protein]PMID:36216167 PMID:36403809
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