GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tgfb1 | affects expression | EXP | | 6480464 | CTD | benazepril affects the expression of TGFB1 mRNA | PMID:16635409 | Tgfb1 | decreases expression | EXP | | 6480464 | CTD | benazepril results in decreased expression of TGFB1 mRNA; benazepril results in decreased expression of TGFB1 protein | PMID:11798627 PMID:11867951 PMID:16191423 PMID:17177138 PMID:19018797 | Tgfb1 | multiple interactions | EXP | | 6480464 | CTD | [benazepril co-treated with candesartan] results in decreased expression of TGFB1 protein; [benazepril co-treated with Irbesartan] affects the expression of TGFB1 mRNA; benazepril inhibits the reaction [Doxorubicin results in increased expression of TGFB1 mRNA]; benazepril inhibits the reaction [Doxorubicin results in increased expression of TGFB1 protein]; benazepril inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein] | PMID:10515446 PMID:16409969 PMID:16523407 PMID:16635409 PMID:19487956 PMID:20493835 PMID:20844835 | Tgfb1 | decreases expression | ISO | TGFB1 (Homo sapiens) | 6480464 | CTD | benazepril results in decreased expression of TGFB1 protein | PMID:18390891 | Tgfb1 | multiple interactions | ISO | TGFB1 (Homo sapiens) | 6480464 | CTD | [benazepril co-treated with Valsartan] results in decreased expression of TGFB1 protein | PMID:18390891 | |
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