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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69051
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tgfb1
Name: transforming growth factor, beta 1
Acc ID: CHEBI:28741
Term: sodium fluoride
Definition: A metal fluoride salt with a Na(+) counterion.
Chemical ID: MESH:D012969
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgfb1increases expressionEXP 6480464CTDSodium Fluoride results in increased expression of TGFB1 mRNA; Sodium Fluoride results in increased expression of TGFB1 proteinPMID:29758312 PMID:37121298
Tgfb1multiple interactionsEXP 6480464CTDprotocatechuic acid methyl ester inhibits the reaction [Sodium Fluoride results in increased expression of TGFB1 mRNA]PMID:29758312
Tgfb1increases expressionISOTgfb1 (Mus musculus)6480464CTDSodium Fluoride results in increased expression of TGFB1 mRNA; Sodium Fluoride results in increased expression of TGFB1 proteinPMID:29505816
Tgfb1multiple interactionsISOTgfb1 (Mus musculus)6480464CTDTGFB1 protein promotes the reaction [Sodium Fluoride results in decreased expression of SQSTM1 mRNA]; TGFB1 protein promotes the reaction [Sodium Fluoride results in decreased expression of SQSTM1 protein]; TGFB1 protein promotes the reaction [Sodium Fluoride results in increased expression of BECN1 mRNA]; TGFB1 protein promotes the reaction [Sodium Fluoride results in increased expression of MAP1LC3B mRNA]PMID:29505816
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