GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Prkcd | affects localization | EXP | | 6480464 | CTD | Methamphetamine affects the localization of PRKCD protein | PMID:24430743 | Prkcd | affects response to substance | EXP | | 6480464 | CTD | PRKCD protein affects the susceptibility to Methamphetamine | PMID:22512859 | Prkcd | increases expression | EXP | | 6480464 | CTD | Methamphetamine results in increased expression of PRKCD protein | PMID:22512859 | Prkcd | increases response to substance | EXP | | 6480464 | CTD | PRKCD results in increased susceptibility to Methamphetamine | PMID:24430743 | Prkcd | multiple interactions | EXP | | 6480464 | CTD | [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased activity of TH protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased expression of DAT protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased expression of SLC18A2 protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in increased metabolism of Dopamine]; [rottlerin results in decreased activity of PRKCD protein] which results in decreased susceptibility to Methamphetamine; ginsenoside Re inhibits the reaction [Methamphetamine affects the localization of PRKCD protein]; Methamphetamine promotes the reaction [PRKCD protein modified form binds to EPHX1 protein]; Methamphetamine results in increased cleavage of and results in increased phosphorylation of PRKCD protein; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of CAT protein]]; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of SOD1 protein]]; PRKCD affects the reaction [Methamphetamine results in increased activity of CAT protein]; PRKCD affects the reaction [Methamphetamine results in increased activity of SOD1 protein]; PRKCD affects the reaction [Methamphetamine results in increased activity of SOD2 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased activity of TH protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of BCL2L1 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of DAT protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of SLC18A2 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of TH protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of EPHX1 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased metabolism of Dopamine] | PMID:22512859 PMID:24430743 PMID:31422080 | Prkcd | affects localization | ISO | PRKCD (Homo sapiens) | 6480464 | CTD | Methamphetamine affects the localization of PRKCD protein | PMID:25523949 | Prkcd | multiple interactions | ISO | PRKCD (Homo sapiens) | 6480464 | CTD | ginsenoside Re inhibits the reaction [Methamphetamine affects the localization of PRKCD protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of and results in increased cleavage of PRKCD protein]; Methamphetamine results in increased expression of and results in increased cleavage of PRKCD protein; PRKCD protein affects the reaction [Methamphetamine affects the localization of PRKCD protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]; PRKCD protein affects the reaction [Methamphetamine results in increased activity of SOD1 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased activity of SOD2 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of and results in increased cleavage of PRKCD protein] | PMID:25523949 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |