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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69006
Species: Homo sapiens
RGD Object: Gene
Symbol: ITGA1
Name: integrin subunit alpha 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ITGA1decreases methylationEXP 6480464CTDbisphenol A results in decreased methylation of ITGA1 genePMID:31601247
ITGA1multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Fulvestrant] affects the methylation of ITGA1 genePMID:31601247
ITGA1decreases expressionISOItga1 (Mus musculus)6480464CTDbisphenol A results in decreased expression of ITGA1 mRNAPMID:34585602
ITGA1increases expressionISOItga1 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of ITGA1 mRNAPMID:25181051 PMID:29097150
ITGA1increases expressionISOItga1 (Mus musculus)6480464CTDbisphenol A results in increased expression of ITGA1 mRNAPMID:26063408 PMID:30951980
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