GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Penk | increases expression | EXP | | 6480464 | CTD | Haloperidol results in increased expression of PENK mRNA | PMID:14603264 PMID:15215559 | Penk | multiple interactions | EXP | | 6480464 | CTD | 3,4-dicarboxyphenylglycine promotes the reaction [Haloperidol results in increased expression of PENK mRNA]; Docosahexaenoic Acids inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; Tretinoin inhibits the reaction [Haloperidol results in increased expression of PENK mRNA] | PMID:14603264 PMID:15215559 | Penk | increases expression | ISO | Penk (Rattus norvegicus) | 6480464 | CTD | Haloperidol results in increased expression of PENK mRNA; Haloperidol results in increased expression of PENK protein | PMID:12373537 PMID:12727308 PMID:12834887 PMID:12887421 PMID:14642644 PMID:17224239 PMID:3838946 PMID:7637876 | Penk | multiple interactions | ISO | Penk (Rattus norvegicus) | 6480464 | CTD | 1-aminocyclopentane-1,2,4-tricarboxylic acid inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; 1-aminoindan-1,5-dicarboxylic acid inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; 2-(2,3-dicarboxycyclopropyl)glycine promotes the reaction [Haloperidol results in increased expression of PENK mRNA]; 5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; Memantine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; Scopolamine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA] | PMID:12373537 PMID:12727308 PMID:12834887 PMID:14642644 PMID:17224239 PMID:7637876 | | ||||||||||||||||||||||
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