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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68534
Species: Mus musculus
RGD Object: Gene
Symbol: Mtor
Name: mechanistic target of rapamycin kinase
Acc ID: CHEBI:6950
Term: mirtazapine
Definition: A tetracyclic antidepressant that has formula C17H19N3.
Chemical ID: MESH:C035133
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mtordecreases phosphorylationISOMtor (Rattus norvegicus)6480464CTDMirtazapine results in decreased phosphorylation of MTOR proteinPMID:35066094
Mtormultiple interactionsISOMtor (Rattus norvegicus)6480464CTDEthanol promotes the reaction [Mirtazapine results in decreased phosphorylation of MTOR protein]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in decreased phosphorylation of MTOR protein]]; HMGB1 protein affects the reaction [Mirtazapine results in decreased phosphorylation of MTOR protein]PMID:35066094
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