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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68534
Species: Mus musculus
RGD Object: Gene
Symbol: Mtor
Name: mechanistic target of rapamycin kinase
Acc ID: CHEBI:4512
Term: Dictamnine
Definition: An alkaloid antibiotic that has formula C12H9NO2.
Chemical ID: MESH:C026398
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mtordecreases phosphorylationISOMTOR (Homo sapiens)6480464CTDdictamnine results in decreased phosphorylation of MTOR proteinPMID:34861243
Mtormultiple interactionsISOMTOR (Homo sapiens)6480464CTD[dictamnine co-treated with Oxygen deficiency] results in decreased phosphorylation of MTOR protein; dictamnine inhibits the reaction [FGF protein results in increased phosphorylation of MTOR protein]PMID:30266538 PMID:34861243
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