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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68534
Species: Mus musculus
RGD Object: Gene
Symbol: Mtor
Name: mechanistic target of rapamycin kinase
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mtoraffects phosphorylationEXP 6480464CTDDiethylnitrosamine affects the phosphorylation of MTOR proteinPMID:24535843
Mtorincreases expressionISOMtor (Rattus norvegicus)6480464CTDDiethylnitrosamine results in increased expression of MTOR mRNAPMID:30423403
Mtormultiple interactionsISOMtor (Rattus norvegicus)6480464CTDneferine inhibits the reaction [Diethylnitrosamine results in increased expression of MTOR mRNA]PMID:30423403
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