GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mtor | decreases activity | EXP | | 6480464 | CTD | sodium arsenite results in decreased activity of MTOR protein | PMID:23143138 | Mtor | decreases expression | EXP | | 6480464 | CTD | sodium arsenite results in decreased expression of MTOR protein modified form | PMID:23143138 | Mtor | affects expression | ISO | MTOR (Homo sapiens) | 6480464 | CTD | sodium arsenite affects the expression of MTOR mRNA | PMID:29319823 | Mtor | decreases expression | ISO | MTOR (Homo sapiens) | 6480464 | CTD | sodium arsenite results in decreased expression of MTOR protein | PMID:27107786 | Mtor | decreases phosphorylation | ISO | MTOR (Homo sapiens) | 6480464 | CTD | sodium arsenite results in decreased phosphorylation of MTOR protein | PMID:29039521 | Mtor | increases expression | ISO | MTOR (Homo sapiens) | 6480464 | CTD | sodium arsenite results in increased expression of MTOR mRNA; sodium arsenite results in increased expression of MTOR protein | PMID:36444808 | Mtor | multiple interactions | ISO | MTOR (Homo sapiens) | 6480464 | CTD | [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased phosphorylation of MTOR protein; [sodium arsenite co-treated with tetrandrine] affects the expression of and affects the phosphorylation of MTOR protein; [sodium arsenite results in increased abundance of arsenite] which results in increased phosphorylation of MTOR protein; MIR21 mRNA affects the reaction [sodium arsenite results in decreased expression of MTOR protein]; PTEN protein affects the reaction [MIR21 mRNA affects the reaction [sodium arsenite results in decreased expression of MTOR protein]]; PTEN protein affects the reaction [sodium arsenite results in decreased expression of MTOR protein]; Sirolimus inhibits the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased phosphorylation of MTOR protein]; sodium arsenite affects the expression of and affects the phosphorylation of MTOR protein; sodium arsenite promotes the reaction [Sirolimus results in decreased expression of MTOR protein]; U 0126 inhibits the reaction [sodium arsenite results in decreased expression of MTOR protein]; Wortmannin inhibits the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased phosphorylation of MTOR protein] | PMID:27107786 PMID:28888487 PMID:30123091 PMID:31781319 PMID:32802178 | | ||||||||||||||||||||||
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