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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68534
Species: Mus musculus
RGD Object: Gene
Symbol: Mtor
Name: mechanistic target of rapamycin kinase
Acc ID: CHEBI:29014
Term: cordycepin
Definition: A 3'-deoxyribonucleoside that has formula C10H13N5O3.
Chemical ID: MESH:C058120
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mtordecreases activityEXP 6480464CTDcordycepin results in decreased activity of MTOR proteinPMID:22537056
Mtorincreases phosphorylationEXP 6480464CTDcordycepin results in increased phosphorylation of MTOR proteinPMID:31145545
Mtormultiple interactionsEXP 6480464CTD4-nitrobenzylthioinosine inhibits the reaction [cordycepin results in decreased activity of MTOR protein]PMID:22537056
Mtoraffects expressionISOMTOR (Homo sapiens)6480464CTDcordycepin affects the expression of MTOR mRNAPMID:36881089
Mtorincreases phosphorylationISOMTOR (Homo sapiens)6480464CTDcordycepin results in increased phosphorylation of MTOR proteinPMID:34070360
Mtormultiple interactionsISOMTOR (Homo sapiens)6480464CTD[cordycepin co-treated with Cisplatin] results in decreased phosphorylation of MTOR proteinPMID:33520990
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