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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68534
Species: Mus musculus
RGD Object: Gene
Symbol: Mtor
Name: mechanistic target of rapamycin kinase
Acc ID: CHEBI:18721
Term: 3-chloropropane-1,2-diol
Definition: A chloropropane-1,2-diol that is propane-1,2-diol substituted by a chloro group at position 3.
Chemical ID: MESH:D000517
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mtordecreases expressionEXP 6480464CTDalpha-Chlorohydrin results in decreased expression of MTOR proteinPMID:33171136
Mtordecreases phosphorylationISOMTOR (Homo sapiens)6480464CTDalpha-Chlorohydrin results in decreased phosphorylation of MTOR proteinPMID:35149085
Mtormultiple interactionsISOMTOR (Homo sapiens)6480464CTD3-methyladenine inhibits the reaction [Diosgenin promotes the reaction [alpha-Chlorohydrin results in decreased phosphorylation of MTOR protein]]; Diosgenin promotes the reaction [alpha-Chlorohydrin results in decreased phosphorylation of MTOR protein]PMID:35149085
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